Job Description

Job Summary

The Huang Laboratory is looking to hire a Research Laboratory Specialist Associate to take on additional lab duties and advance specific projects within the lab. Located in the Division of Pulmonary and Critical Care Medicine in the Department of Internal Medicine at the University of Michigan Medical School, our laboratory studies how epigenetic modifications contribute to the development of pulmonary fibrosis and other chronic lung diseases. We obtain lung tissue from patients with pulmonary fibrosis and healthy controls from Gift of Life, Michigan and study how fibroblasts and other cell types acquire changes in DNA methylation to contribute to lung fibrosis. Some of our current projects include investigating how DNA methyltransferases and Ten-eleven translocation enzymes regulate DNA methylation in lung fibroblasts, studying how different populations of fibroblasts differ in their DNA methylation patterns, and determining how methylation in fibroblasts might be regulated by tissue stiffness and mediators such as prostaglandin E2. The PI is additional in charge of maintaining the interstitial lung disease tissue biorepository and some of the work will involve processing biospecimens when they arrive. Preparation of lung tissue will involve digestion, cell isolation, positive and negative cell selection, cell culture, and generation of precision-cut lung slices. The Research Laboratory Specialist is expected to help plan and set up experiments using patient-derived cells, perform immunoblot, PCR, immunofluorescence/histochemistry, and learn techniques for epigenetic analysis. Individuals will be expected to collect and organize data and share findings with the PI. We strive to be diverse, inclusive, and respectful to all members of the research community.

Mission Statement

Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally.  Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.

Why Join Michigan Medicine?

Michigan Medicine is one of the largest health care complexes in the world and has been the site of many groundbreaking medical and technological advancements since the opening of the U-M Medical School in 1850. Michigan Medicine is comprised of over 30,000 employees and our vision is to attract, inspire, and develop outstanding people in medicine, sciences, and healthcare to become one of the world’s most distinguished academic health systems.  In some way, great or small, every person here helps to advance this world-class institution. Work at Michigan Medicine and become a victor for the greater good.

What Benefits can you Look Forward to?

Responsibilities*

Conducting experiments and advancing specific projects

With assistance and input from the PI, plan, design, and execute lab-bench type experiments involving:

Help organize and manage the Interstitial Lung Disease (ILD) Biorepository

Required Qualifications*

Bachelor's degree or greater in the biological sciences with at least 1-3 years experience.

Desired Qualifications*

Master's Degree preferred.

Modes of Work

Positions that are eligible for hybrid or mobile/remote work mode are at the discretion of the hiring department. Work agreements are reviewed annually at a minimum and are subject to change at any time, and for any reason, throughout the course of employment. Learn more about the work modes.

Background Screening

Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings.  Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.

Application Deadline

Job openings are posted for a minimum of seven calendar days.  The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.

U-M EEO/AA Statement

The University of Michigan is an equal opportunity/affirmative action employer.

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